Cardiovascular risk factors and all-cause mortality in the elderly

In elderly, smoking and heart rate predict all-cause mortality

In elderly men from Finland, The Netherlands and Italy, age, smoking and heart rate were positively associated with excess 10-year all-cause mortality. The association of systolic blood pressure with all-cause mortality was marginally significant at 10 years. HDL-cholesterol and body mass index were significantly inversely related to all-cause mortality after 10 years of follow-up but these associations were no longer significant after excluding early deaths (during the first 5 years of follow-up).These results suggest that smoking and heart rate (an indicator of physical activity and fitness) remain useful risk factors in prediction of all-cause mortality up to old age.

About the FINE study

In 1984, the SCS field surveys were extended with different aspects of health in the FINE (Finland Italy Netherlands Elderly) study. Similar surveys were also carried out in Serbia and Crete. Read more about the FINE study.

More about healthy aging

From 1984 onwards, additional studies started to examine indicators of healthy ageing in the elderly populations of in the SCS and related studies.


Telomeres and all-cause mortality

Longer telomeres at baseline did not predict all-cause mortality, even though telomere shortening is a marker of aging that might be related to oxidative stress.

Chronic diseases and all-cause mortality

The relations of different chronic diseases with all-cause mortality was studied from middle-age onwards in the Seven Countries Study and in old age in the FINE Study.